Do Pheromone Sprays work?

Before I answer this question let me give the definetion

Pheromone: an odorous substance or smell secreted by an organism that acts as a chemical messenger between members of the same or different species and serves as a foe repellent, territorial boundary or path marker, social heriarchy position indicator, child-parent bonding agent, or sexual lover/lover mate attractant. Pheromones may also regulate the reproductive ecology within a given species; an odoriferous substance that acts as a chemical messenger between individuals. By contrast, a hormone acts as a chemical messenger within the bloodstream of a single individual. In mammals, pheromones serve as foe repellents, boundary markers, child-parent attractants, and sex [lover-lover] attractants.

Some commercially-available substances are advertised using claims that the products contain sexual pheromones and can act as an aphrodisiac. These often lack credibility due to an excessive marketing of pheromones by unsolicited e-mail. Moreover, despite claims to the contrary, no defined pheromonal substance has ever been demonstrated to influence human behaviour in a peer reviewed, published study.

Nevertheless, a few well-controlled scientific studies have been published demonstrating the possibility of pheromones in humans. The best-studied case involves the synchronization of menstrual cycles among women based on unconscious odor cues (the so called McClintock effect, named after the primary investigator). This study states that there are two types of pheromone involved: "One, produced prior to ovulation, shortens the ovarian cycle, and the second, produced just at ovulation, lengthens the cycle". This is analogous to the Whitten effect, a male pheromone mediated modulation of estrus observed in mice. Other studies have suggested that people might be using odor cues associated with the immune system to select mates who are not closely related to themselves.
In 2006 it was shown that a second mouse receptor sub-class is found in the olfactory epithelium. Called the trace amine-associated receptors (TAAR), some are activated by volatile compounds found in mouse urine, including one putative pheromone. Orthologous receptors exist in humans providing, the authors propose, evidence for a mechanism of human pheromone detection.

Human pheromones are postulated to be produced by the apocrine glands. The apocrine glands become functional after reaching puberty which, it is hypothesized, could contribute to people developing a sexual attraction for others at that time. Pheromone detection has also been proposed to be the reason why a person can sense "chemistry", or feel an instant attraction or dislike when first meeting someone. Using a brain imaging technique, Swedish researchers have shown that homosexual and heterosexual men respond differently to two odours that may be involved in sexual arousal, and that the gay men respond in the same way as women. This research suggests a possible role for human pheromones in the biological basis of sexual orientation.